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Typically we position the mouse at the right (or left) of the keyboard.
This placement is not the easiest place to reach, however. Having 'extra keys' to the right of the letter and number keys (for example, arrow keys, insert, page down and the number pad) do not allow users to place the mouse more directly in line with their arm and shoulder. Reaching your arm forward or sideways beyond an "easy reach" zone can lead to these discomfort and even injury. Please see the OSH Answers document Computer Mouse: Common Problems from Use for more information.
There is no right or wrong place for a mouse. Rather, you must properly assess your work space to make sure you can use the keyboard and mouse without excessive leaning or reaching which may cause discomfort to the body.
Some computer workstations (Figure 2) do not have enough space to properly position a mouse, but a space must be made so that the workstation is safe and comfortable. One way to make this space is by using a mouse platform. Another way to make this space is by using a shorter keyboard (for example, one without a number pad).
When there is not enough space on the desk to position a mouse within easy reach, you can use a mouse platform. A mouse platform covers the numerical pad on the right side of the keyboard - which is rarely used in many office functions - and serves as a place for the mouse to sit. (Figure 2). The mouse is then closer to the person using it. As well, because the mouse is on a platform, you avoid the tendency to wiggle it further and further away, which would make you reach even further and increase muscle strain.
However, the height of the mouse platform puts your hand in a slightly unnatural position. To make using it more comfortable, you can use a forearm support. (Figure 3).
Computer keyboards come in many sizes. By using a shorter (35.6 cm or 14" long) keyboard instead of a regular (45.7 cm or 18" long) one, you will have an extra 10.2 cm or 4 inches of space beside the keyboard where the mouse can be placed (Figure 4).
Note: Whatever shape, size, or application of mouse you use, a battery-powered cordless mouse is highly recommended. It eliminates one of the most common problems with using a mouse: the cord getting stuck or being in the way.